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Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvelous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich night life and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities on the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Rome to Athens
 Saturday 21st September 2024
Departing Rome (Civitavecchia)  
 14 Nights
 Nieuw Statendam
Discounted Fares  Discounted Fares
 Sale Fare
 Twin From $2,667 pp
 Single From $5,036 pp
Mediterranean
 Sunday 22nd September 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Odyssey Of The Seas
Award Winning Ships  Award Winning Ships
 Amazing Included Value
 Twin From $4,194 pp
 Quad From $2,889 pp
Rome to Barcelona
 Monday 23rd September 2024
Departing Rome (Civitavecchia)  
 12 Nights
 Celebrity Ascent
 Premium Cruise Line
 Twin From $10,175 pp
 Quad From $7,365 pp
Italy, France & Spain
 Tuesday 24th September 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $4,362 pp
 Quad From $3,901 pp
Italy, Spain & France
 Tuesday 24th September 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Norwegian Escape
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $3,239 pp
 Single From $6,203 pp
Italy, Turkey & Greece
 Thursday 26th September 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Carnival Legend
Choose Fun  Choose Fun
 Family Cruise Line
 Twin From $1,788 pp
 Quad From $1,145 pp
Italy & Greece
 Thursday 26th September 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
 Amazing Included Value
 Twin From $1,708 pp
 Single From $2,944 pp
Rome to Barcelona
 Thursday 26th September 2024
Departing Rome (Civitavecchia)  
 3 Nights
 Oasis Of The Seas
Award Winning Ships  Award Winning Ships
 Amazing Included Value
 Twin From $967 pp
 Quad From $796 pp
Greece, Izmir & Naples
 Friday 27th September 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $2,478 pp
 Quad From $2,246 pp
Italy, Spain & France
 Sunday 29th September 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,741 pp
 Quad From $1,542 pp
Rome to Barcelona
 Sunday 29th September 2024
Departing Rome (Civitavecchia)  
 11 Nights
 Seabourn Ovation
 Twin From $9,009 pp
Rome to Barcelona
 Sunday 29th September 2024
Departing Rome (Civitavecchia)  
 21 Nights
 Seabourn Ovation
 Twin From $16,064 pp
Italy, France & Spain
 Tuesday 1st October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $4,381 pp
 Quad From $3,892 pp
Italy, Greece & Turkey
 Tuesday 1st October 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Odyssey Of The Seas
Award Winning Ships  Award Winning Ships
 Amazing Included Value
 Twin From $5,094 pp
 Quad From $3,527 pp
Spain, Cannes & Italy
 Wednesday 2nd October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $2,013 pp
 Quad From $2,658 pp
Rome to Trieste (Venice)
 Thursday 3rd October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Norwegian Escape
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $3,236 pp
 Quad From $6,262 pp
Greece, Izmir & Naples
 Friday 4th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $6,545 pp
 Quad From $5,017 pp
Italy, Spain & France
 Sunday 6th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,848 pp
 Quad From $2,066 pp
Italy & Croatia
 Monday 7th October 2024
Departing Rome (Civitavecchia)  
 11 Nights
 Celebrity Constellation
 Premium Cruise Line
 Twin From $2,921 pp
 Quad From $2,422 pp
Italy, France & Spain
 Tuesday 8th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $2,216 pp
 Quad From $1,751 pp
Spain, Cannes & Italy
 Wednesday 9th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $3,070 pp
 Quad From $2,420 pp
Greece, Izmir & Naples
 Friday 11th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $1,916 pp
 Quad From $2,270 pp
Rome to Barcelona
 Saturday 12th October 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Celebrity Equinox
 Premium Cruise Line
 Triple From $2,474 pp
 Quad From $2,332 pp
Italy, Spain & France
 Sunday 13th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $3,499 pp
 Quad From $4,071 pp
Rome to Barcelona
 Monday 14th October 2024
Departing Rome (Civitavecchia)  
 12 Nights
 Celebrity Ascent
 Premium Cruise Line
 Twin From $4,717 pp
 Quad From $4,021 pp
Italy, France & Spain
 Monday 14th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Luxury Large Ship Cruises
 Twin From $1,838 pp
 Quad From $2,323 pp
Italy, France & Spain
 Tuesday 15th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $2,032 pp
 Quad From $2,357 pp
Greece, Izmir & Naples
 Friday 18th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $2,081 pp
 Quad From $2,066 pp
Turkey, Greece & Cyprus
 Saturday 19th October 2024
Departing Rome (Civitavecchia)  
 8 Nights
 Explorer Of The Seas
Award Winning Ships  Award Winning Ships
 Amazing Included Value
 Twin From $3,766 pp
 Quad From $2,627 pp
Italy, Spain & France
 Sunday 20th October 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $5,225 pp
 Quad From $4,052 pp