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Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvelous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich night life and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities on the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Spain, Cannes & Italy
 Wednesday 1st May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $5,447 pp
 Quad From $4,171 pp
Italy, Spain & Marseille
 Sunday 5th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $5,029 pp
 Quad From $3,948 pp
Rome (Civitavecchia) to Trieste (Venice)
 Monday 6th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Viva
 Twin From $2,338 pp
 Quad From $3,406 pp
Italy, France & Spain
 Tuesday 7th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $1,731 pp
 Quad From $1,513 pp
Spain, Cannes & Italy
 Wednesday 8th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,537 pp
 Quad From $1,896 pp
Greece, Malta and Italy
 Thursday 9th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $2,067 pp
 Quad From $3,021 pp
Italy & Spain
 Thursday 9th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Oasis Of The Seas
 Amazing Included Value
 Twin From $2,457 pp
 Quad From $1,835 pp
Greece, Izmir & Naples
 Friday 10th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $2,866 pp
 Quad From $2,367 pp
Italy, Spain & Marseille
 Sunday 12th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $3,380 pp
 Quad From $3,909 pp
Italy, Croatia & Montenegro
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 11 Nights
 Celebrity Constellation
 Premium Cruise Line
 Twin From $2,216 pp
 Quad From $1,279 pp
Greece & Turkey
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 14 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $3,491 pp
 Triple From $3,194 pp
Rome (Civitavecchia) to Istanbul
 Monday 13th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $1,648 pp
 Single From $2,884 pp
Italy, France & Spain
 Tuesday 14th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $1,460 pp
 Quad From $1,518 pp
Spain, Cannes & Italy
 Wednesday 15th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,615 pp
 Quad From $1,518 pp
France, Italy & Spain
 Thursday 16th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Oasis Of The Seas
 Amazing Included Value
 Twin From $2,215 pp
 Quad From $1,566 pp
Greece, Izmir & Naples
 Friday 17th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $2,013 pp
 Quad From $2,095 pp
Italy, Greece & Kusadasi (Ephesus)
 Friday 17th May 2024
Departing Rome (Civitavecchia)  
 9 Nights
 Odyssey Of The Seas
 Amazing Included Value
 Twin From $3,491 pp
 Quad From $2,463 pp
Rome (Civitavecchia) to Piraeus (Athens)
 Saturday 18th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Sun Princess
 Twin From $3,481 pp
 Quad From $2,415 pp
Italy, Spain & Marseille
 Sunday 19th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,693 pp
 Quad From $1,959 pp
Greece, Malta and Italy
 Sunday 19th May 2024
Departing Rome (Civitavecchia)  
 10 Nights
 Norwegian Epic
Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
 Amazing Included Value
 Twin From $2,037 pp
 Quad From $2,991 pp
Italy, France & Spain
 Monday 20th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Luxury Large Ship Cruises
 Twin From $1,440 pp
 Quad From $2,241 pp
Italy, France & Spain
 Tuesday 21st May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $1,693 pp
 Quad From $3,696 pp
Spain, Cannes & Italy
 Wednesday 22nd May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,644 pp
 Quad From $1,838 pp
Italy & Spain
 Thursday 23rd May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Oasis Of The Seas
 Amazing Included Value
 Twin From $1,567 pp
 Quad From $1,433 pp
Greece, Izmir & Naples
 Friday 24th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Divina
 Luxury Large Ship Cruises
 Twin From $1,654 pp
 Quad From $1,601 pp
Italy, Spain & Marseille
 Sunday 26th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaside
 Luxury Large Ship Cruises
 Twin From $1,567 pp
 Quad From $1,848 pp
Mediterranean
 Monday 27th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 Queen Victoria
Cunard Sale  Cunard Sale
 Premium Cruise Line
 Twin From $1,842 pp
 Triple From $1,722 pp
Italy, France & Spain
 Monday 27th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Musica
 Luxury Large Ship Cruises
 Twin From $1,363 pp
 Quad From $1,290 pp
Italy, France & Spain
 Tuesday 28th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Fantasia
 Luxury Large Ship Cruises
 Twin From $1,460 pp
 Quad From $1,542 pp
Spain, Cannes & Italy
 Wednesday 29th May 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Seaview
 Luxury Large Ship Cruises
 Twin From $1,634 pp
 Quad From $1,969 pp